Eraserhead
I saw it in a theater full of straight couples.
I don't know, there are four options: either they're asexual, they're concerned about chastity, they drool over the "uniqueness" of their elevated taste in cinema, or they had no idea what they were about to see, because I can't wrap my head around the idea of someone deliberately taking their girlfriend to a film that screams, "USE THOSE DAMN CONDOMS!"
Also one girl asked her chaperon when the end credits started rolling: So...she did not actually give birth to that alien, or what?